Prednisolone Acetate (Ophthalmic): Uses,Dosage,Side Effects | MedexInfo

Prednisolone Acetate (Ophthalmic)

Rx Only

Generic NamePrednisolone Acetate

Therapeutic ClassCorticosteroid

Common Dose1–2 drops in affected eye(s) 2–4 times daily

Max / 24hAs per ophthalmologist guidance

PregnancyCategory C

Indications ▼

Inflammatory ocular conditions (e.g., uveitis, conjunctivitis)

Postoperative ocular inflammation

Allergic eye diseases causing significant inflammation

Mechanism & Pharmacokinetics ▼

Mechanism: Binds to glucocorticoid receptors in ocular tissues, reducing inflammatory mediator production and immune response.

Pharmacokinetics: Minimal systemic absorption; primarily acts locally on ocular tissues; metabolized in cornea and aqueous humor; excreted via tear fluid and drainage.

Dosage & Administration ▼

Patient Category	Recommended Dose	Max / 24h
Adults	1–2 drops in affected eye(s) 2–4 times daily	Follow ophthalmologist guidance
Elderly	Same as adults; monitor for intraocular pressure changes	Follow ophthalmologist guidance
Children	1 drop in affected eye(s) 2–3 times daily; adjust per specialist	Follow ophthalmologist guidance

Note: Shake well before use. Avoid contact with tip of the dropper. Taper per ophthalmologist instructions for prolonged therapy.

Side Effects ▼

Ocular irritation, burning, or stinging

Increased intraocular pressure, risk of glaucoma

Cataract formation with long-term use

Secondary ocular infections

Contraindications ▼

Viral, bacterial, or fungal ocular infections (unless concurrently treated)

Hypersensitivity to prednisolone or other corticosteroids

Caution in patients with glaucoma or ocular hypertension

Drug Interaction ▼

Concurrent ocular NSAIDs may increase irritation

Systemic CYP3A4 inhibitors/inducers may slightly alter systemic levels if absorbed

Other ocular medications may require staggered administration

Pregnancy & Lactation ▼

Use only if benefits outweigh risks; systemic exposure is minimal

Excreted in breast milk in very small amounts; generally considered compatible

Clinical / Research Summary ▼

Effective in controlling ocular inflammation and reducing postoperative complications

Rapid symptom relief in uveitis, conjunctivitis, and allergic eye disease

Well-documented in ophthalmology clinical trials and guidelines

Patient Counseling Points ▼

Wash hands before administration; avoid touching dropper tip to eye

Use exactly as prescribed; do not stop abruptly if using long-term

Report vision changes, eye pain, or signs of infection immediately

Storage & Handling ▼

Store at 20–25°C (68–77°F)

Protect from light; keep tightly closed

Keep out of reach of children

Brand Names (Bangladesh & Global) ▼

Bangladesh:

Bexipred® 1% Eye Drops Biocort® 1% Eye Drops Cortan® 1% Eye Drops Cortisol® 1% Eye Drops Edisolone® 1% Eye Drops Isolon® 1% Eye Drops Ocusol® 1% Eye Drops Pednisol® 1% Eye Drops Precodil® 1% Eye Drops Pred® 1% Eye Drops Predflam® 1% Eye Drops Prednol® 1% Eye Drops Renisol® 1% Eye Drops Sterolon® 1% Eye Drops

Global:

Pred Forte® Prednisolone Acetate Ophthalmic

Medical Disclaimer: This information is for educational purposes only. Consult a healthcare provider for professional guidance.

Reference Hubs:

• Drug Class: Corticosteroids • Condition: Ocular Inflammatory Diseases • Pathway: Glucocorticoid Receptor Modulation • Clinical Evidence & Trials