Tiemonium Methylsulfate 50 mg

Rx

Generic NameTiemonium Methylsulphate

Therapeutic ClassAntispasmodic / Anticholinergic

Common Dose20–30 mg orally 3–4 times daily

PregnancyUse only if clearly needed

Indications ▼

Irritable Bowel Syndrome (IBS) with abdominal cramps or spasms

Functional gastrointestinal disorders with smooth muscle spasms

Adjunct therapy in biliary or renal colic

Mechanism & Pharmacokinetics ▼

Mechanism: Tiemonium methylsulphate is an anticholinergic that inhibits muscarinic receptors in smooth muscle, reducing spasms and motility in the gastrointestinal tract.

Pharmacokinetics: Rapidly absorbed orally; metabolized in the liver; excreted mainly via urine. Onset: 30–60 minutes orally, faster with injection.

Dosage & Administration ▼

Form	Dose	Frequency
Oral Tablet	20–30 mg	3–4 times daily before meals
Oral Solution	20–30 mg	3–4 times daily
Injection (IM/IV)	10–20 mg	As needed for severe spasms

Note: Adjust dose for elderly or patients with severe renal/hepatic impairment.

Side Effects ▼

Dry mouth, blurred vision

Constipation, urinary retention

Palpitations, tachycardia (rare)

Dizziness or headache

Allergic skin reactions (rare)

Contraindications ▼

Hypersensitivity to tiemonium or other anticholinergics

Obstructive uropathy or severe urinary retention

Glaucoma (narrow-angle)

Myasthenia gravis

Severe ulcerative colitis or paralytic ileus

Drug Interaction ▼

Other anticholinergic drugs: additive effects (dry mouth, urinary retention)

Potentiation of CNS depressants (e.g., sedatives)

May reduce effect of cholinesterase inhibitors

Pregnancy & Lactation ▼

Use only if clearly needed; limited human data available

Breastfeeding: caution advised, monitor infant for anticholinergic effects

Clinical / Research Summary ▼

Clinical Role: Effective antispasmodic for gastrointestinal smooth muscle disorders.

Advantage: Rapid onset, multiple routes (oral & injection), generally well-tolerated.

Monitoring: Watch for urinary retention, dry mouth, or tachycardia in sensitive patients.

Patient Counseling Points ▼

Take before meals if oral

Avoid driving if dizzy or drowsy

Report urinary retention or severe constipation

Do not combine with other anticholinergics without consulting a doctor

Storage & Handling ▼

Store below 25–30°C

Protect from moisture and light

Keep out of reach of children

Brand Names (Bangladesh & Global) ▼

Bangladesh:

Algin® 50 mg Tablet Algin® 10 mg/5 ml Syrup Algin® 5 mg/2 ml Injection Tienum® 50 mg Tablet Emonium® 50 mg Tablet Tynium® 10 mg/5 ml Syrup Norvis® 50 mg Tablet Timonac® 50 mg Tablet Timonac® 5 mg/2 ml Injection Deltimo® 50 mg Tablet

Global:

Tiemonium Methylsulphate (generic)

Medical Disclaimer: For educational purposes only. Not a substitute for professional medical advice.

Reference Hubs:

• Drug Class: Antispasmodics • Condition: Irritable Bowel Syndrome • Condition: Gastrointestinal Cramps