Sodium Cromoglicate: Uses, Dosage, Side Effects | MedexInfo

Sodium Cromoglicate

Rx/OTC

Generic NameSodium Cromoglicate

Therapeutic ClassMast Cell Stabilizer

Common Strength2%, 4% eye drops; 2 mg/spray nasal; 20 mg capsules

PregnancyGenerally considered safe

Indications ▼

Allergic Conjunctivitis: Prevention and relief of itching, redness, and watery eyes caused by allergens.

Allergic Rhinitis: Symptomatic relief of sneezing, nasal itching, and runny nose due to seasonal or perennial allergies.

Exercise-Induced Bronchospasm: Prevention of asthma attacks triggered by physical exertion.

Mastocytosis: Management of symptoms associated with abnormal mast cell activation.

Mechanism & Pharmacokinetics ▼

Mechanism: Stabilizes mast cell membranes, preventing release of histamine and other inflammatory mediators, thus reducing allergic symptoms.

Pharmacokinetics: Poorly absorbed systemically when given topically; acts locally at site of administration. Onset may take several days for maximal effect in chronic therapy.

Dosage & Administration ▼

Indication	Dose	Frequency
Allergic conjunctivitis (eye drops)	1–2 drops per eye	4 times daily
Allergic rhinitis (nasal spray)	1–2 sprays per nostril	3–4 times daily
Exercise-induced bronchospasm	20 mg capsule	4 times daily, 1–2 hours before exercise

Note: Use regularly for optimal effect; may require 1–2 weeks for maximum relief.

Side Effects ▼

Mild eye or nasal irritation

Cough, throat irritation, or headache (inhalation)

Rare: hypersensitivity reactions

Contraindications ▼

Hypersensitivity to sodium cromoglicate or excipients

Drug Interaction ▼

No significant systemic drug interactions reported due to minimal absorption.

Pregnancy & Lactation ▼

Generally considered safe; consult physician before use

Clinical / Research Summary ▼

Clinical Role: Preventive therapy for allergic conditions, especially in eyes, nose, and respiratory tract.

Advantage: Non-steroidal, minimal systemic absorption, safe for long-term use.

Limitation: Delayed onset; not suitable for acute symptom relief.

Monitoring: Observe for local irritation or hypersensitivity reactions.

Patient Counseling Points ▼

Use regularly for best effect

Do not stop abruptly without consulting physician

Report eye/nasal irritation or allergic reactions

For exercise-induced bronchospasm, take before physical activity

Storage & Handling ▼

Store below 25°C

Protect from light and moisture

Keep out of reach of children

Brand Names (Bangladesh & Global) ▼

Bangladesh:

Mastguard Drops Cromolin Drops Sodicrom 2% Drops Sodicrom DS 4% Drops Novacrom Drops Optacrom Drops Itchin DS Drops

Global:

Intal®

Medical Disclaimer: For educational purposes only. Not a substitute for professional medical advice.

Reference Hubs:

• Drug Class: Mast Cell Stabilizers • Condition: Allergic Rhinitis • Condition: Allergic Conjunctivitis