Travoprost: Uses, Dosage, Side Effects & Brands | MedexInfo

Travoprost

Rx

Generic NameTravoprost

Therapeutic ClassProstaglandin Analog (Ophthalmic)

Common Strength0.004% ophthalmic solution

Max / 24h1 drop in affected eye(s) once daily in the evening

PregnancyUse only if benefit outweighs risk

Indications ▼

Open-angle glaucoma

Ocular hypertension

Mechanism & Pharmacokinetics ▼

Mechanism: Travoprost is a prostaglandin F2α analog that increases uveoscleral outflow of aqueous humor, reducing intraocular pressure.

Pharmacokinetics: Applied topically, absorbed through the cornea, rapidly hydrolyzed to active free acid. Peak effect within 12 hours. Metabolized in liver, excreted mainly via urine.

Dosage & Administration ▼

Indication	Dose	Frequency
Adults (Glaucoma / Ocular hypertension)	1 drop in affected eye(s)	Once daily in the evening

Note: Do not exceed once daily; apply in the evening for optimal efficacy.

Side Effects ▼

Ocular hyperemia (redness)

Itching, burning, or stinging sensation

Increased eyelash growth

Darkening of iris or periocular skin

Rare: eye pain, blurred vision

Contraindications ▼

Hypersensitivity to travoprost or any component

Active ocular infection or inflammation

Drug Interaction ▼

Other ocular hypotensive drugs: additive effect on IOP

Systemic prostaglandins: potential interaction unlikely

Pregnancy & Lactation ▼

Use only if clearly needed; no adequate human data

Unknown if excreted in breast milk; caution advised

Clinical / Research Summary ▼

Clinical Role: First-line topical therapy for lowering intraocular pressure in glaucoma and ocular hypertension.

Advantage: Once-daily dosing; effective IOP reduction.

Limitation: Local ocular side effects; long-term iris color changes.

Monitoring: Intraocular pressure, ocular irritation, eyelash/iris changes.

Patient Counseling Points ▼

Apply 1 drop in affected eye(s) in the evening

Avoid touching tip of bottle to eye or fingers

Report persistent redness, pain, or vision changes

Remove contact lenses before administration; wait 15 minutes before reinsertion

Storage & Handling ▼

Store unopened at 2–8°C; room temperature after opening

Protect from light

Keep out of reach of children

Brand Names (Bangladesh & Global) ▼

Bangladesh:

Avatan® 0.004% Eye Drops Avost® 0.004% Eye Drops Avro® 0.004% Eye Drops Optaprost® 0.004% Eye Drops Trapost OSD® 0.004% Eye Drops Travagen Z® 0.004% Eye Drops Travast® 0.004% Eye Drops Travofix® 0.004% Eye Drops Travolar® 0.004% Eye Drops Uniprost® 0.004% Eye Drops

Global:

Travatan® Z

Medical Disclaimer: For educational purposes only. Not a substitute for professional medical advice.

Reference Hubs:

• Drug Class: Prostaglandin Analogs • Condition: Glaucoma