Vitamin-B Complex & Vitamin C
OTC / Rx
Generic NameVitamin-B Complex & Vitamin C
Therapeutic ClassVitamin / Multivitamin
Max / 24hAs per individual vitamin limits (Vitamin C: 2 g oral, B6: 100 mg, others within RDA)
Common DoseOne tablet daily or as prescribed
PregnancyGenerally safe (Category A)
Indications ▼
Prevention and treatment of vitamin B and C deficiencies
Support for energy metabolism and nervous system function
Adjunct antioxidant therapy
Support during pregnancy, lactation, and chronic illnesses
Mechanism & Pharmacokinetics ▼
Mechanism: B vitamins act as cofactors in enzymatic reactions essential for energy production, neurotransmitter synthesis, and red blood cell formation. Vitamin C supports collagen synthesis, antioxidant defense, and immune function.
Pharmacokinetics: B vitamins and vitamin C are water-soluble, absorbed in the small intestine. Excess amounts are excreted via urine. Peak plasma levels within 1–3 hours for most vitamins.
Dosage & Administration ▼
| Vitamin | Recommended Dose | Frequency |
|---|---|---|
| Vitamin B1 (Thiamine) | 1.1–1.2 mg | Daily |
| Vitamin B2 (Riboflavin) | 1.1–1.3 mg | Daily |
| Vitamin B6 (Pyridoxine) | 1.3–2 mg | Daily |
| Vitamin B12 (Cyanocobalamin) | 2.4 µg | Daily |
| Niacinamide | 14–16 mg | Daily |
| Folic Acid | 400 µg | Daily |
| Vitamin C | 50–500 mg | Daily |
Note: Administer orally with meals; IM/IV route for deficiencies or malabsorption. Avoid exceeding recommended daily allowance unless prescribed.
Side Effects ▼
Nausea, upset stomach, diarrhea (high doses)
Flushing or warmth (niacinamide / B3)
Peripheral neuropathy (very high doses of B6)
Kidney stones (rare, high Vitamin C doses)
Contraindications ▼
Known hypersensitivity to any vitamin component
Caution in patients with history of kidney stones (Vitamin C) or neuropathy (B6)
Drug Interaction ▼
High doses may affect laboratory glucose and urine tests
Vitamin C may increase absorption of iron
Vitamin B6 may reduce efficacy of levodopa (without carbidopa)
Pregnancy & Lactation ▼
Generally safe within recommended doses (Category A)
Excreted in breast milk; safe in lactation at standard doses
Clinical / Research Summary ▼
Therapeutic Role: Supports energy metabolism, nerve function, red blood cell formation, collagen synthesis, and antioxidant defense.
Clinical Effectiveness: Prevents vitamin deficiency, supports immunity, enhances wound healing, reduces fatigue, and maintains neurological health.
Safety Profile: Well tolerated at recommended doses; monitor high-dose B6 and C to avoid neuropathy and kidney stones.
Current Research: Investigating high-dose vitamin C in immune modulation and chronic disease support, and B-complex in energy metabolism and neurological conditions.
Patient Counseling Points ▼
Take with meals to improve absorption and reduce GI upset
Do not exceed recommended daily dose unless prescribed
Inform healthcare provider about kidney or neuropathy history
Can be taken with iron supplements for better absorption
Storage & Handling ▼
Store at room temperature, protect from light and moisture
Keep out of reach of children
Brand Names (Bangladesh & Global) ▼
Bangladesh (Local Brands):
Global / International Brands:
Medical Disclaimer: This information is intended for educational purposes only and must not replace professional medical advice.