Urea 10% Ointment: Uses, Dosage, Side Effects & Brands | MedexInfo

Urea 10%

OTC

Generic NameUrea

Therapeutic ClassKeratolytic / Moisturizer

Max / 24hApply 2–3 times daily

Common DoseThin layer applied to affected areas 1–3 times daily

PregnancyUse if benefit outweighs risk; topical use generally considered safe

Indications ▼

Dry, rough, scaly skin conditions

Eczema and dermatitis

Psoriasis and ichthyosis

Keratoderma and hyperkeratotic lesions

Mechanism & Pharmacokinetics ▼

Mechanism: Urea acts as a humectant and keratolytic agent, increasing water content in the stratum corneum and softening thickened skin.

Pharmacokinetics: Minimal systemic absorption when applied topically; metabolized locally in skin; excreted via normal skin turnover.

Dosage & Administration ▼

Condition	Recommended Dose	Frequency
Dry / rough skin	Thin layer	1–3 times daily
Hyperkeratotic lesions	Apply and gently rub	1–2 times daily

Note: Avoid applying to open wounds or infected skin; wash hands after application.

Side Effects ▼

Mild burning, stinging, or itching at application site

Redness or irritation

Rare: Allergic contact dermatitis

Contraindications ▼

Hypersensitivity to urea or any component of the formulation

Open wounds, infected or eczematous skin (unless advised by physician)

Drug Interaction ▼

No significant systemic drug interactions known due to minimal absorption

Pregnancy & Lactation ▼

Topical use generally considered safe; use only if necessary and benefit outweighs risk

Excretion in breast milk negligible; use with caution on nursing infants

Clinical / Research Summary ▼

Therapeutic Role: Moisturizes and softens hyperkeratotic and dry skin conditions.

Clinical Effectiveness: Improves skin hydration, reduces scaling, and restores smoothness in keratotic disorders.

Safety Profile: Generally well tolerated; local irritation may occur but systemic effects are rare.

Current Research: Studies focus on optimized concentration for skin barrier restoration and combination with other emollients.

Patient Counseling Points ▼

Apply only to intact skin; avoid mucous membranes

Wash hands after each application

Do not cover treated areas with occlusive dressings unless advised

Discontinue if severe irritation or allergic reaction occurs

Maintain regular application for best results

Storage & Handling ▼

Store at room temperature (20–25°C), away from moisture and light

Keep out of reach of children

Brand Names (Bangladesh & Global) ▼

Bangladesh (Local Brands):

Eucera® 10% Eudrate® 10% Uramed® 10% Aqua Care® 10% Eukrim® 10% Equra® 10% Eusoft® 10%

Global / International Brands:

Keralac Ureacin

Medical Disclaimer: This information is intended for educational purposes only and must not replace professional medical advice.

Reference Hubs:

• Drug Class: Keratolytics / Moisturizers • Conditions: Dry Skin / Xerosis • Conditions: Hyperkeratotic Skin Disorders