Fluticasone Propionate (Topical): Uses, Dosage, Side Effects | MedexInfo

Fluticasone Propionate (Topical)

Rx

Generic NameFluticasone Propionate

Therapeutic ClassTopical Corticosteroid

Max / 24hApply thin layer twice daily

Common DoseOnce or twice daily

PregnancyUse if benefit outweighs risk

Indications ▼

Atopic dermatitis (eczema)

Contact dermatitis (allergic or irritant)

Seborrheic dermatitis

Psoriasis (localized, mild to moderate)

Lichen simplex chronicus

Inflammatory dermatoses responsive to corticosteroids

Relief of erythema, itching, and skin inflammation

Mechanism & Pharmacokinetics ▼

Mechanism: Suppresses inflammatory mediators by inhibiting phospholipase A2 activity, reducing prostaglandins and leukotrienes, and decreasing capillary permeability.

Pharmacokinetics: Minimal systemic absorption when applied topically. Metabolized in the liver; excreted mainly in bile and urine.

Dosage & Administration ▼

Condition	Recommended Use	Frequency
Dermatitis / Eczema	Thin layer on affected area	Once or twice daily
Psoriasis (localized)	Thin layer	Once daily

Note: Use the smallest effective amount. Avoid occlusive dressing unless prescribed.

Side Effects ▼

Skin thinning (atrophy)

Burning or stinging sensation

Dryness, irritation

Hypopigmentation

Rare: Systemic corticosteroid effects with prolonged use

Contraindications ▼

Untreated bacterial, viral, or fungal skin infections

Hypersensitivity to corticosteroids

Rosacea and perioral dermatitis

Drug Interaction ▼

Concomitant topical steroids increase risk of skin atrophy

Occlusive dressings increase systemic absorption

Pregnancy & Lactation ▼

Use lowest effective dose during pregnancy

Avoid prolonged use on large surface areas

Safe in lactation if not applied on breast area

Clinical / Research Summary ▼

Clinical Role: Medium-potency topical corticosteroid for inflammatory skin disorders.

Effectiveness: Rapid relief of itching and inflammation.

Safety: Safe when used short-term under medical supervision.

Research Focus: Optimized dosing to minimize steroid-related adverse effects.

Patient Counseling Points ▼

Apply thin layer only to affected skin

Do not use on face, groin, or armpits unless advised

Avoid long-term continuous use

Wash hands after application

Storage & Handling ▼

Store below 30°C

Protect from direct sunlight

Keep tightly closed

Brand Names (Bangladesh & Global) ▼

Bangladesh:

Cutisone® 0.05% Cutisone® 0.005% Flupion® 0.005% Flupro® 0.05% Flutica® 0.05% Fluticare® 0.05% Fluticare® 0.005% Flutiderm® 0.005% Flutivate® 0.05% Fluvate® 0.005% Lutisone® 0.005% T-Cort® 0.05% Ticas® 0.05% Ticason® 0.05% Ticason® 0.005%

Global:

Cutivate Flonase (topical derivatives)

Medical Disclaimer: This information is intended for educational purposes only and must not replace professional medical advice.

Reference Hubs:

• Drug Class: Topical Corticosteroids • Conditions: Dermatitis • Conditions: Psoriasis