Potassium Citrate + Citric Acid: Uses, Dosage, Side Effects | MedexInfo

Potassium Citrate + Citric Acid

Rx / OTC

Generic NamePotassium Citrate + Citric Acid

Therapeutic ClassUrinary Alkalinizer

Common Dose10–30 mL 2–3 times daily

Max / 24h100 mEq potassium

PregnancyCategory C

Indications ▼

Prevention and treatment of uric acid kidney stones

Prevention of calcium oxalate nephrolithiasis

Renal tubular acidosis

Adjunct therapy in gout with uric acid crystalluria

Mechanism & Pharmacokinetics ▼

Mechanism: Metabolized to bicarbonate, increasing urinary pH and reducing urinary calcium excretion. Enhances citrate excretion which binds calcium, preventing stone formation.

Pharmacokinetics: Rapid oral absorption; metabolized in liver to bicarbonate. Excess potassium excreted via kidneys. Onset within hours; urinary alkalinization maintained with regular dosing.

Dosage & Administration ▼

Patient Category	Recommended Dose	Max / 24h
Adults	10–30 mL orally 2–3 times daily after meals	100 mEq potassium
Children	1–3 mEq/kg/day in divided doses	As prescribed
Renal Impairment	Use cautiously; monitor serum potassium	Individualized

Note: Dilute solution in a full glass of water before administration. Monitor serum potassium and urinary pH regularly.

Side Effects ▼

Common: Nausea, vomiting, abdominal discomfort

Occasional: Diarrhea, bloating

Rare: Hyperkalemia, cardiac arrhythmias, metabolic alkalosis

Contraindications ▼

Hyperkalemia

Severe renal impairment

Untreated Addison’s disease

Delayed gastric emptying or esophageal compression

Drug Interaction ▼

ACE inhibitors / ARBs: increased risk of hyperkalemia

Potassium-sparing diuretics: additive hyperkalemia risk

Anticholinergics: delayed GI transit increases irritation risk

Pregnancy & Lactation ▼

Category C; use only if clearly needed

Generally considered safe in normal potassium balance; monitor levels

Clinical / Research Summary ▼

Effectively reduces recurrence of uric acid and calcium oxalate stones.

Maintains urinary pH above 6.0, reducing uric acid crystallization.

Long-term therapy requires monitoring of electrolytes and renal function.

Patient Counseling Points ▼

Dilute before taking; do not take undiluted solution.

Take after meals to reduce stomach upset.

Maintain adequate fluid intake.

Report muscle weakness or irregular heartbeat immediately.

Storage & Handling ▼

Store at room temperature (20–25°C)

Keep container tightly closed

Brand Names (Bangladesh & Global) ▼

Bangladesh:

Alcasol® Oral Solution Alkamax® Oral Solution Alken® Oral Solution Alkurin® Oral Solution Citra-K® Oral Solution Citrosol® Oral Solution CK OS® Oral Solution Kcit® Oral Solution Potacit® Oral Solution Ural-K® Oral Solution Ureca® Oral Solution Uri-K® Oral Solution Urifine® Oral Solution Urikal® Oral Solution Urilizer® Oral Solution Urinor® Oral Solution Uriset® Oral Solution Urocid-N® Oral Solution Urodel-K® Oral Solution Urokit Plus® Oral Solution Urokool® Oral Solution Urosolv® Oral Solution Urotrate® Oral Solution

Global:

Urocit-K® Potassium Citrate Solution (Generic)

Medical Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult a qualified healthcare provider.

Reference Hubs:

• Drug Class: Urinary Alkalinizers • Condition: Nephrolithiasis • Clinical Evidence & Trials