Zinc Oxide Ointment: Uses, Dosage, Side Effects & Brands | MedexInfo

Zinc Oxide Ointment

OTC

Generic NameZinc Oxide

Therapeutic ClassProtective / Skin Barrier

Common DoseApply thin layer 1–3 times daily

PregnancyUse with caution; topical application considered low risk

Indications ▼

Minor burns, cuts, and abrasions

Diaper rash and mild skin irritation

Mild dermatitis and eczema

Sunburn protection and skin barrier maintenance

Mechanism & Pharmacokinetics ▼

Mechanism: Forms a protective barrier on skin, reflecting moisture and acting as a mild astringent. Promotes healing and reduces irritation.

Pharmacokinetics: Minimal systemic absorption when applied topically; acts locally at site of application. Excreted via normal skin desquamation.

Dosage & Administration ▼

Condition	Recommended Dose	Frequency
Minor burns / cuts / abrasions	Thin layer	1–3 times daily
Diaper rash	Apply generously	With each diaper change
Mild dermatitis / eczema	Thin layer	1–3 times daily or as needed

Note: Clean and dry the affected area before application; avoid contact with eyes and mucous membranes.

Side Effects ▼

Mild skin irritation, redness, or itching

Rare: Allergic contact dermatitis

Extensive use may cause temporary skin whitening at site of application

Contraindications ▼

Known hypersensitivity to zinc oxide or any formulation excipients

Open deep wounds or severe skin infections (unless advised by physician)

Drug Interaction ▼

No clinically significant interactions known with topical use

Pregnancy & Lactation ▼

Topical use considered low risk; avoid ingestion

Use during breastfeeding is generally safe

Clinical / Research Summary ▼

Therapeutic Role: Acts as a protective barrier for irritated skin, promotes healing and reduces moisture-induced damage.

Clinical Effectiveness: Widely used for diaper rash, minor burns, and mild dermatitis; effective in reducing erythema and discomfort.

Safety Profile: Excellent safety record; minimal systemic absorption and rare allergic reactions.

Current Research: Studies focus on barrier enhancement, combined formulations with emollients or antiseptics for enhanced efficacy.

Patient Counseling Points ▼

Apply only to intact skin; clean area before use.

Avoid contact with eyes and mucous membranes.

Discontinue if irritation or rash develops; seek medical advice.

Use as directed for diaper rash, burns, or dermatitis.

Store at room temperature away from moisture and light.

Storage & Handling ▼

Store at 20–25°C, protect from moisture and light

Keep out of reach of children

Brand Names (Bangladesh & Global) ▼

Bangladesh (Local Brands):

De-rash® Calzin

Global / International Brands:

Desitin Bepanthen

Medical Disclaimer: This information is intended for educational purposes only and must not replace professional medical advice.

Reference Hubs:

• Drug Class: Skin Protective Agents • Conditions: Diaper Rash • Conditions: Mild Dermatitis