Zinc Orotate
OTC
Generic NameZinc Orotate
Therapeutic ClassMineral Supplement
Elemental Zinc10–20 mg
Common DoseOnce daily
PregnancySafe (Recommended dose)
Indications ▼
Treatment and prevention of zinc deficiency
Growth retardation in children
Acute and persistent diarrhea
Impaired immunity and recurrent infections
Delayed wound healing
Skin disorders including acne and dermatitis
Hair loss and brittle nails
Malnutrition and chronic illness support
Mechanism & Pharmacokinetics ▼
Mechanism: Zinc is an essential trace element involved in more than 300 enzymatic reactions. It supports DNA synthesis, cell division, immune response, antioxidant defense and intestinal mucosal repair. Zinc orotate improves cellular absorption due to the orotic acid carrier.
Pharmacokinetics: Absorbed mainly in the small intestine. Bioavailability is influenced by dietary phytates. Zinc is widely distributed in tissues and excreted primarily through feces.
Dosage & Administration ▼
| Patient Group | Dose | Duration |
|---|---|---|
| Adults | 10–20 mg elemental zinc | Once daily |
| Children | 10 mg | Once daily |
| Diarrhea | 10–20 mg | 10–14 days |
Side Effects ▼
Nausea
Metallic taste
Abdominal discomfort
Vomiting (high dose)
Long-term excessive use may cause copper deficiency
Contraindications ▼
Hypersensitivity to zinc preparations
Chronic high-dose zinc therapy without monitoring
Drug Interaction ▼
Tetracyclines and quinolones: reduced absorption
Penicillamine: reduced therapeutic effect
Iron and calcium reduce zinc absorption
Pregnancy & Lactation ▼
Safe during pregnancy at recommended dose
Essential for fetal growth and immunity
Compatible with breastfeeding
Clinical / Research Summary ▼
Zinc plays a critical role in immune modulation and epithelial repair.
WHO recommends zinc supplementation in childhood diarrhea.
Clinical studies show reduced duration and severity of diarrhea.
Zinc deficiency is common in malnutrition and chronic illness.
Patient Counseling Points ▼
Take after meals to reduce stomach upset
Avoid taking with iron or calcium at the same time
Do not exceed recommended dose long term
Complete full course in diarrhea treatment
Storage & Handling ▼
Store below 30°C
Protect from moisture and light
Keep out of reach of children
Brand Names (Bangladesh & Global) ▼
Bangladesh:
Global:
Square Zinc® 20
Medical Disclaimer: This content is for educational purposes only and must not replace professional medical advice.
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