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Vinpocetine: Uses, Dosage, Side Effects & Brands | MedexInfo

Vinpocetine: Uses, Dosage, Side Effects & Brands | MedexInfo

Vinpocetine

Rx
Generic NameVinpocetine
Therapeutic ClassCerebral Vasodilator / Neuroprotective
Max / 24h30 mg
Common Dose5–10 mg orally 3 times daily or as prescribed
PregnancyUse only if benefit outweighs risk
Indications ▼
Cerebrovascular disorders (stroke recovery, ischemic conditions)
Memory and cognitive impairment
Dizziness and vertigo
Adjunct therapy in neurodegenerative conditions
Mechanism & Pharmacokinetics ▼
Mechanism: Enhances cerebral blood flow by vasodilation, improves oxygen and glucose utilization in neurons, and exhibits neuroprotective effects by inhibiting phosphodiesterase and protecting against oxidative stress.
Pharmacokinetics: Rapidly absorbed orally; peak plasma concentration within 1 hour. Widely distributed in the body including the brain. Metabolized hepatically, primarily excreted via urine and bile. Half-life ~2–4 hours.
Dosage & Administration ▼
ConditionRecommended DoseFrequency
General cognitive support / cerebrovascular disorder5–10 mgOrally 3 times daily
Stroke recovery / neurological deficit10 mgOrally 3 times daily or IV as prescribed
Note: Take with meals to reduce gastrointestinal discomfort. Adjust dose for elderly or renal/hepatic impairment as per physician guidance.
Side Effects ▼
Gastrointestinal discomfort (nausea, heartburn)
Headache, dizziness
Hypotension in sensitive patients
Rare: Allergic reactions, palpitations
Contraindications ▼
Hypersensitivity to Vinpocetine or vinca alkaloids
Severe hypotension or cardiovascular instability
Pregnancy or breastfeeding unless directed by physician
Drug Interaction ▼
Antihypertensive drugs: additive hypotensive effect
Anticoagulants / antiplatelets: monitor for bleeding risk
CYP3A4 substrates: possible interaction
Pregnancy & Lactation ▼
Use only if benefit outweighs risk
Consult physician before breastfeeding
Clinical / Research Summary ▼
Therapeutic Role: Cerebral vasodilator for improving brain perfusion and neuroprotection.
Clinical Effectiveness: May improve cognitive function, memory, and recovery post-stroke or ischemic events.
Safety Profile: Generally well tolerated; monitor blood pressure and cardiovascular status.
Current Research: Evaluating neuroprotective potential in dementia, stroke, and other cognitive disorders.
Patient Counseling Points ▼
Take with meals to reduce nausea
Monitor for dizziness or hypotension
Do not exceed recommended dose
Inform healthcare provider of all medications
Storage & Handling ▼
Store below 25°C in a dry place
Protect from light and moisture
Keep out of reach of children
Brand Names (Bangladesh & Global) ▼
Bangladesh (Local Brands): Global / International Brands:
Medical Disclaimer: This information is intended for educational purposes only and must not replace professional medical advice.

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