Vitamin E: Uses, Dosage, Side Effects & Brands | MedexInfo

Vitamin E

OTC / Rx

Generic NameVitamin E

Therapeutic ClassFat-soluble Vitamin

Max / 24h1000 mg (oral), 150 IU/kg (IV in deficiency)

Common Dose15 mg (22.4 IU) daily for adults

PregnancyUse only if benefit outweighs risk (Category C)

Indications ▼

Vitamin E deficiency

Antioxidant support to reduce oxidative stress

Support cardiovascular health

Support immune function

Adjunct therapy in certain dermatological conditions

Mechanism & Pharmacokinetics ▼

Mechanism: Acts as a lipid-soluble antioxidant, protecting cell membranes from oxidative damage by scavenging free radicals. Supports immune function and enzymatic reactions.

Pharmacokinetics: Absorbed in the small intestine with dietary fats, transported in chylomicrons. Stored in adipose tissue and liver. Metabolized in the liver and excreted in bile and urine.

Dosage & Administration ▼

Condition	Recommended Dose	Frequency
Adult deficiency / supplementation	15 mg (22.4 IU)	Once daily orally
High-dose antioxidant therapy	100–400 IU	Daily orally as prescribed
IV therapy for severe deficiency	10–25 IU/kg	Once daily as needed

Note: Administer with meals for better absorption. Avoid exceeding recommended doses to prevent toxicity.

Side Effects ▼

Nausea, diarrhea, abdominal cramps

Fatigue, headache

Increased risk of bleeding at high doses

Rare: Allergic reactions or rash

Contraindications ▼

Hypersensitivity to Vitamin E or any excipients

Vitamin K deficiency or anticoagulant therapy caution

Severe liver disease (caution with high doses)

Drug Interaction ▼

Anticoagulants (warfarin, heparin): increased bleeding risk

Statins: may reduce vitamin E levels

Oral contraceptives may slightly increase serum vitamin E

Pregnancy & Lactation ▼

Use only if benefit outweighs risk (Category C)

Excreted in breast milk; generally safe in recommended doses

Clinical / Research Summary ▼

Therapeutic Role: Protects against oxidative stress, supports cardiovascular, immune, and neurological health.

Clinical Effectiveness: Effective in correcting deficiency; mixed results in cardiovascular prevention studies.

Safety Profile: Well tolerated at recommended doses; high doses increase bleeding risk.

Current Research: Investigating effects on neurodegenerative disorders, cardiovascular disease, and dermatologic conditions.

Patient Counseling Points ▼

Take with meals containing fat for better absorption

Do not exceed recommended doses

Inform your doctor if taking anticoagulants

Report unusual bleeding or bruising

Storage & Handling ▼

Store at room temperature, protect from light and moisture

Keep out of reach of children

Brand Names (Bangladesh & Global) ▼

Bangladesh (Local Brands):

Evit™ Soft Evion Tocovita

Global / International Brands:

Evion Nature Made Vitamin E Solgar Vitamin E

Medical Disclaimer: This information is intended for educational purposes only and must not replace professional medical advice.

Reference Hubs:

• Drug Class: Fat-soluble Vitamins • Conditions: Vitamin E Deficiency • Conditions: Oxidative Stress