Tenoxicam: Uses, Dosage, Side Effects & Brands | MedexInfo

Tenoxicam

Rx

Generic NameTenoxicam

Therapeutic ClassNSAID (Oxicam group)

Common Dose20 mg once daily

Max / 24h20 mg

PregnancyAvoid (especially 3rd trimester)

Indications ▼

Rheumatoid arthritis

Osteoarthritis

Ankylosing spondylitis

Acute musculoskeletal pain

Postoperative and post-traumatic pain

Acute gout (short-term use)

Mechanism & Pharmacokinetics ▼

Mechanism: Tenoxicam inhibits cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis. This results in analgesic, anti-inflammatory, and antipyretic effects.

Pharmacokinetics: Well absorbed orally. Highly protein bound. Long elimination half-life of about 60–75 hours allowing once-daily dosing. Metabolized in the liver and excreted mainly via urine and bile.

Dosage & Administration ▼

Indication	Dose	Frequency
Arthritis (RA, OA, AS)	20 mg	Once daily
Acute pain	20 mg	Once daily (short term)
Injection	20 mg	IM or IV once daily

Note: Use the lowest effective dose for the shortest possible duration.

Side Effects ▼

Dyspepsia, abdominal pain

Nausea, vomiting

Gastritis, peptic ulcer, GI bleeding

Headache, dizziness

Fluid retention, edema

Rare: renal impairment, hypersensitivity reactions

Contraindications ▼

History of NSAID-induced asthma or allergy

Active peptic ulcer or GI bleeding

Severe heart failure

Severe renal or hepatic impairment

Third trimester of pregnancy

Drug Interaction ▼

Anticoagulants and antiplatelets: increased bleeding risk

Corticosteroids: increased GI ulcer risk

ACE inhibitors and diuretics: reduced antihypertensive effect

Other NSAIDs: increased adverse effects

Lithium and methotrexate: increased toxicity

Pregnancy & Lactation ▼

Avoid during pregnancy, especially in the third trimester

May cause premature closure of ductus arteriosus

Use during lactation only if clearly necessary

Clinical / Research Summary ▼

Clinical Role: Long-acting NSAID suitable for chronic inflammatory joint diseases.

Advantage: Once-daily dosing improves patient adherence.

Limitation: Higher GI and renal risk with long-term use.

Monitoring: GI symptoms, renal function, blood pressure.

Patient Counseling Points ▼

Take after food to reduce stomach irritation

Avoid combining with other painkillers unless advised

Report black stools or severe stomach pain immediately

Do not use for long periods without medical supervision

Storage & Handling ▼

Store below 30°C

Protect from light and moisture

Keep out of reach of children

Brand Names (Bangladesh & Global) ▼

Bangladesh:

Enocam® 20 mg Inoten® 20 mg Mobicam® 20 mg Oxicam® 20 mg Oxiflam® 20 mg Raditil® 20 mg Tenoflex® 20 mg Tenopain® 20 mg Tenorix® 20 mg Tenoxim® 20 mg Texicam® 20 mg Xicotil® 20 mg Xten® 20 mg

Global:

Tilcotil

Medical Disclaimer: For educational purposes only. Not a substitute for professional medical advice.

Reference Hubs:

• Drug Class: NSAIDs • Condition: Arthritis • Condition: Pain Management