Beclometasone Dipropionate: Uses, Dosage, Side Effects & Brands | MedexInfo
Beclometasone Dipropionate
Rx Only
Therapeutic ClassCorticosteroid (Glucocorticoid)
Common Dose100–200 mcg per inhalation (2–4 times daily)
PregnancyCategory C
Indications ▼
Asthma (maintenance therapy)
Chronic obstructive pulmonary disease (COPD) adjunct therapy
Allergic rhinitis and nasal polyps (nasal spray)
Prevention of exercise-induced bronchospasm
Mechanism & Pharmacokinetics ▼
Mechanism: Binds to glucocorticoid receptors, suppressing inflammatory cytokines, reducing airway inflammation and hyperreactivity.
Absorption: Low systemic bioavailability via inhalation; higher when swallowed.
Distribution: Widely distributed in respiratory tissue.
Metabolism: Extensively metabolized in the liver to inactive metabolites.
Excretion: Primarily in urine as metabolites.
Dosage & Administration ▼
| Indication | Recommended Dose |
|---|---|
| Asthma (Adults) | 100–200 mcg 2–4 times daily via metered-dose inhaler |
| Asthma (Children) | 40–160 mcg 2 times daily |
| Allergic Rhinitis (Nasal Spray) | 1–2 sprays per nostril once daily |
Rinse mouth after inhalation to prevent oral candidiasis.
Side Effects ▼
Common: Oral thrush, hoarseness, mild cough
Occasional: Headache, throat irritation, nausea
Rare: Adrenal suppression, growth retardation (long-term in children), glaucoma, cataracts
Contraindications ▼
Hypersensitivity to beclometasone or other corticosteroids
Acute asthma attacks (not for emergency relief)
Untreated systemic infections
Drug Interaction ▼
CYP3A4 inhibitors may increase systemic corticosteroid levels
Concomitant immunosuppressants may increase infection risk
Other inhaled corticosteroids: additive effects possible
Pregnancy & Lactation ▼
Category C – use only if benefits outweigh risk
Minimal systemic absorption via inhalation; compatible with breastfeeding
Clinical / Research Summary ▼
Effective in reducing airway inflammation and asthma symptoms with chronic use.
Improves lung function, reduces frequency of exacerbations.
Long-term studies show favorable safety in inhaled doses compared to systemic steroids.
Adjunct therapy with beta-agonists enhances bronchodilation and symptom control.
Patient Counseling Points ▼
Use daily for maintenance; not for acute attacks.
Rinse mouth after use to prevent fungal infection.
Do not stop abruptly if used long-term; consult doctor for tapering.
Report vision changes, throat pain, or persistent cough.
Storage & Handling ▼
Store below 30°C, away from moisture and sunlight
Keep inhaler upright and cap closed
Brand Names (Bangladesh & Global) ▼
Bangladesh:
Global:
BecloventQvar
Beclomethasone
Clenil
Medical Disclaimer: This content is for educational purposes only and does not replace professional medical advice.
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