Amlexanox: Dosage, Side Effects, Brands & Clinical Use | MedexInfo

Amlexanox

Rx Only

Therapeutic ClassAnti-inflammatory / Anti-allergic agent

Common Dose2–5% topical paste or cream, applied 3–4 times daily

Max / 24hFollow product-specific instructions (usually up to 4 applications/day)

PregnancyCategory B – Use if benefit outweighs risk

Indications ▼

Recurrent aphthous ulcers (canker sores)

Minor oral inflammatory lesions

Topical management of oral pain and inflammation

Mechanism & Pharmacokinetics ▼

Mechanism: Inhibits release of inflammatory mediators from mast cells and leukocytes, reducing local inflammation and promoting healing.

Pharmacokinetics: Minimal systemic absorption. Local effect primarily at the site of application.

Dosage & Administration ▼

Patient Category	Recommended Dose	Max / 24h
Adults & Children ≥2 yrs	Apply thin layer of 2–5% paste to ulcer 3–4 times daily	4 applications/day

Side Effects ▼

Common: Mild local burning or stinging sensation

Rare: Local irritation, hypersensitivity reactions

Systemic adverse effects are uncommon due to minimal absorption

Contraindications ▼

Hypersensitivity to Amlexanox or any excipients

Open wounds or severe infections at application site

Drug Interactions ▼

No significant systemic drug interactions reported

Pregnancy & Lactation ▼

Category B – Use topically only if clearly needed

Limited data in breastfeeding; topical use likely low risk

Patient Counseling Points ▼

Apply only to affected area; avoid swallowing excessive amounts

Wash hands before and after application

Avoid using on large or infected lesions

Report persistent pain or ulcer worsening

Storage & Handling ▼

Store at 20–25°C, protect from light and moisture

Keep out of reach of children

Clinical / Research Summary ▼

Topical Amlexanox 5% paste accelerates healing and reduces pain in recurrent aphthous ulcers

Clinical studies demonstrate significant reduction in ulcer duration compared to placebo

Generally well-tolerated with minimal adverse effects

Brand Names (Bangladesh & Global) ▼

Bangladesh (Local Brands):

Amlorax Amlexan

Global / International Brands:

Aphthasol Amlexanox Paste

Medical Disclaimer: This summary is for informational purposes only. Follow guidance from a qualified healthcare professional.

Reference Hubs:

• Drug Class: Anti-inflammatory / Anti-allergic • Conditions: Recurrent Aphthous Ulcers • Pathway: Inhibition of Inflammatory Mediators • Clinical Evidence & Trials