Betamethasone Dipropionate
Rx Only
Generic:Betamethasone Dipropionate
Therapeutic ClassTopical Corticosteroid
Common DoseApply thin layer 1–2 times daily
Max / 24hAs directed by Physician
PregnancyCategory C
Indications ▼
Eczema and dermatitis
Psoriasis (mild to moderate)
Allergic skin reactions
Inflammatory skin conditions requiring potent topical corticosteroids
Mechanism & Pharmacokinetics ▼
Mechanism: Binds to glucocorticoid receptors, modulating gene expression to suppress inflammation, pruritus, and edema in affected skin.
Pharmacokinetics: Minimal systemic absorption with topical use; metabolized in the skin and liver; excreted in urine. Half-life not clinically significant for topical application.
Dosage & Administration ▼
| Patient Category | Recommended Dose | Max / 24h |
|---|---|---|
| Adults | Apply thin layer 1–2 times daily | As directed |
| Children | Use minimal quantity under supervision; avoid prolonged use | As directed |
Apply only to affected areas; avoid face, eyes, and mucous membranes unless prescribed.
Side Effects ▼
Local: Burning, stinging, dryness, irritation, folliculitis
Prolonged use: Skin atrophy, striae, telangiectasia, secondary infection
Rare systemic: HPA axis suppression, hypercortisolism
Contraindications ▼
Hypersensitivity to betamethasone or formulation components
Untreated bacterial, fungal, or viral skin infections
Open wounds or ulcerated skin
Drug Interaction ▼
Other topical corticosteroids may increase risk of local side effects
Systemic corticosteroids can affect HPA axis monitoring
Pregnancy & Lactation ▼
Use only if clearly needed (Category C)
Minimal absorption; caution advised during breastfeeding
Clinical / Research Summary ▼
Efficacy: Potent anti-inflammatory effect reduces redness, itching, and swelling in various dermatoses.
Safety: Topical use generally safe; monitor for skin thinning and local adverse effects during prolonged therapy.
Research Focus: Optimizing dosing regimens and combination with emollients for enhanced efficacy and tolerability.
Patient Counseling Points ▼
How to apply: Apply thin layer to affected area 1–2 times daily; avoid sensitive areas
Missed dose: Apply as soon as remembered; do not double dose
Possible side effects: Local irritation, dryness, burning; monitor for skin changes
Monitor: Long-term use may cause skin atrophy; consult physician if prolonged therapy required
Drug interactions: Avoid other strong topical corticosteroids without guidance
Pregnancy and safety: Use only if prescribed; minimal absorption but caution advised
Storage & Handling ▼
Store at 20–25°C; protect from light and moisture
Keep out of reach of children
Brand Names (Bangladesh & Global) ▼
Betameson
Betam
Betagel
Betnovate
Diprosone
Medical Disclaimer: This clinical summary is for informational purposes only. Always follow guidance from a qualified healthcare professional for dosage, interactions, and use.
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